What can we image?
We can image everything from whole tissue samples and biopsies to organoids and cell cultures. By preserving the native 3D structure, our method reveals cellular and subcellular details that are otherwise lost in sectioned samples. We image almost any organ or disease, and have deep expertise in several areas, particularly kidney disease.
Kidney disease
Visualize and quantify glomeruli, podocytes, and microstructures in 3D across scales.
Other organs & diseases
Visualize and quantify structural changes across organs and disease models in 3D.
How does our technology differ from standard methods?
Current methods are limited by low sensitivity and lack of molecular detail, which can lead to missed diagnostic insights. Our methods deliver 3D, high-throughput, quantitative imaging with molecular precision, offering superior diagnostic power and data-rich insights.
Current methods
Our methods
2D
Qualitative
Low data throughput
Lack of molecular specificity
3D
Quantitative
High data throughput
Molecular specificity
Familiar with confocal microscopy?
Confocal microscopy is a powerful tool, but its resolution often limits the visualization of subcellular structures. Our super-resolution approach goes beyond these limits to reveal nanoscale details and 3D organization within intact tissue while remaining compatible with standard sample preparation.
Confocal
Our method (STED)
How does the service work?
First, we consult to understand your needs and confirm what results you can expect from us.
Testimonials
Q32 Bio has collaborated with Magnephy on several preclinical studies, and the experience has been outstanding. Magnephy brought a wealth of expertise to the table, carefully listening to the scientific questions we were trying to ask and suggesting potential solutions. During study execution the work was excellent, the communication prompt and clear, with regular check-ins to make sure they fully understood our needs and offers to modify the approach as the data emerged.
In the end, the results far exceeded even our most optimistic expectations, providing us with much deeper insight into the podocyte dynamics in our experiments and helping us quantify these effects. Moreover, the images Magnephy generated were breathtaking, providing a truly intuitive understanding of the underlying biology. This really was a case where a picture says a thousand words.
Without hesitation, we highly recommend Magnephy for their expertise in high resolution microscopy, their attention to their customers’ needs, and their ability to deliver rigorous and high impact scientific data. They are a fabulous group of scientists and Q32 Bio looks forward to continuing our collaboration with them.
Preclinical Research and Translational Biology
