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Discover Our Research

Deep learning–based segmentation and quantification of podocyte foot process morphology suggests differential patterns of foot process effacement across kidney pathologies

David Unnersjö-Jess, et al., – 2023

A fast and simple clearing and swelling protocol for 3D in-situ imaging of the kidney across scales

David Unnersjö-Jess, et al., – 2021

Super-resolution stimulated emission depletion imaging of slit diaphragm proteins in optically cleared kidney tissue

David Unnersjö-Jess, et al., – 2016

David Unnersjö

David showed the first ever optical visualization of podocyte foot processes and the slit diaphragm in 2016, and has since then published several papers in high impact journals which describe novel imaging and analysis protocols which have meant a leap forward in the field of kidney imaging.

Portrait of Magnephy’s CTO, a biophysics expert specializing in advanced light microscopy.

Hans Blom

Hans Blom is Docent in Biological Physics at KTH (Royal Institute of Technology), and Head of Unit for Integrated Microscopy Technologies at SciLifeLab, Stockholm.  

He obtained his M.Sc. in Engineering Physics from Uppsala University, and his Ph.D. in Biophotonics from KTH (in collaboration with Karolinska Institutet) in 2003. After post-doctoral work (including in the Nobel Laureate Stefan W. Hell’s group at the Max-Planck Institute), he has focused on super-resolution microscopy and its applications in cell biology, neuroscience, cancer, and specifically kidney pathology.  

His current research aims to include the development of 3D optical imaging of kidney tissue (with nanoscale resolution), improving imaging pipelines for pathological evaluation, collaborations with clinical nephrology, and using microscopy to inform precision medicine.  

Portrait of Magnephy’s scientific co-founder with expertise in super-resolution microscopy.

Featured in

News from Karolinska Institutet: 3D kidney diagnostics using advanced light microscopy

SciLifeLab: Industry case: Early 3D kidney diagnostics development with Magnephy using SciLifeLab advanced light microscopy

SUPPORTED BY

Badge showing that Magnephy’s technology was founded at and supported by KTH Innovation.
Sting accelerator logo, representing Magnephy’s participation in the leading Nordic startup incubator.
NVIDIA Inception Program logo, showing Magnephy’s membership in the AI and deep tech startup program.
Vinnova support badge, indicating Magnephy’s funding from Sweden’s national innovation agency.
SciLifeLab logo, highlighting that Magnephy’s super-resolution microscopy technology originated at SciLifeLab.
SISP logo, showing Magnephy’s connection to Swedish Incubators and Science Parks.
MedTechLabs, Region Stockholm, Karolinska Institutet & KTH Royal Institute of Technology initiative supporting Magnephy.

Fakultetsgränd 8, 114 19 Stockholm, Sweden

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Magnephy logo representing nanoscale 3D microscopy for pharmaceutical development.

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